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Lewes, Delaware
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August 14, 1998     Cape Gazette
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August 14, 1998

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CAPE GAZETTE, Friday, August 14 - August 20, 1998 - 33 / AIDS treatment potpourri: what's noteworthy By Sean C. Venable AIDS treatment has come a long way since the days when AZT was the only medication and the ELISA was the only HIV-re- lated test available. Nonetheless, with no apparent cure waiting in the wings, the key today, as echoed at the World AIDS Conference, is to - as the song suggests - "...keep on keep- ing on." Personally, I've always believed that this is the way to go, regard- less of the ob- stacles. How- ever, at no other time during tile epidemic has it been more im- portant to be pa- tient and com- VENABLE pliant to one's drug regimen than today. As the review below will indi- cate, this is also a time of opti- mism, albeit a cautious one. Remune TM. An immune-based treatment Dr. Jonas Salk, the scientist who developed the polio vaccine, spent his last years of life working on HIV infection and how best to control it. According to Salk's colleague, Dr. Ronald Moss of the Immune Response Corporation, Cancer support group meets Aug. 27 at Kent The We Can Cope cancer sup- port group will hold its monthly meeting from 7 to 9 p.m., Thurs- day, Aug. 27. The meeting will be held at Bayhealth Medical Center-Kent General Hospital, in the Outpa- tient Services Center, General Foods Conference Center, Dover. We Can Cope is for cancer pa- tients, their families and friends. Meetings are open to anyone in- terested in cancer and its manage- ment. The public is invited to at- tend. For more information, call 302-674-71"35. Fitness Tip of the Week Mammography van will visit KSI Sept. 1 Mammography of Delawar&s mobile breast cancer screening van will be at Kent-Sussex Indus- tries Inc., 301 North Rehoboth Blvd., Milford, on Tuesday, Sept. 1. To schedule an appointment, call 800-654-0606. Bosom Buddies meets Aug. 18 at Beebe Beebe Medical Center sponsors Bosom Buddies at 3 p.m., every third Tuesday. The next meeting will be Aug. 18 in the Tunnell "...the fact that the immune sys- tem has already had an initial bat- tle with the virus means there are memory cells in the immune sys- tem that can be restimulated to re- emerge and battle the virus again." This essentially was Salk's thinking and from it came Remune. Briefly, here's how it works: early on in the HIV infection, the virus is combatted by one's im- mune system by special "fighting" T cells and other factors that work against the virus, but eventually the virus prevails and overwhelms these cells and factors and conse- quently, the system. In people who are infected but who do not develop AIDS - called nonpro- gressors - these special cells retain their memory of HIV and contin- ue to function well in combatting HIV. Therefore, in combination with Highly Active Antiretroviral Therapy (HAART), the so-called "drug cocktail" that controls the amount of virus in the blood- stream, it is thought that infected people's immune systems can be returned to systems that look very much like the nonprogressors. In other words, HAART controls the amount of old virus in the blood and Remune would control the newly replicated virus - a self-sur- veillance, if you will. Cancer Center conference room. The support group is for women living with breast cancer, whether they are newly diagnosed, current- ly undergoing treatment or are Iongtime survivors. Call 645- 3770 for more information. FreeBl The American Heart Association is offering free blood pressure screenings in August. Screenings are as follows: Tuesday, Aug. 18 . Rehoboth Edgehill, 10 a.m. - I p.m. Lewes Edgehill 1:30 - 4:30 p.m. Wednesday, Aug. 19 Nanticoke Crossing Edgehill, !:30 - 4:30 p.m. Peddlers Village Edgehill, 10 a.m. - I p.m. Satiety Foods that satisfy your hunger and blood sugar levels will leave you less likely to snack. Eating five meals a day keeps your blood sugar levels elevated and does not allow you to get hungry. By con- suming your highest calorie meal nearly two hours before you train, you will have the greatest energy levels during training, and the smallest prior to inactive periods. Sabmitted by Dave Kergaard Personal fitness trainer For more information, call 227-8095 Other than the above, Remune is significant for the following reasons: Although the immune system must be continuously stimulated, Remune is easy to administer with an intramuscular injection every three months that minimizes ad- herence and intolerability prob- lems, It also would allow a pa- tient to stay on well-tolerated and simpler drug regimens - HAART - longer. Since Remune works best with a viral load - a measurement of less than 100,000 of the amount of virus per mL of blood, patients taking and adherence to drug regi- mens are most important. I sim- ply cannot resist: "You gotta have HAART, miles and miles of HAART .... " Although Remune continues to be tested in clinical trials, it is available via an expanded-access program. T-20- A fusion inhibitor This is the first in a new class of drugs and is very exciting in terms of preventing new infections of the immune systems' T cells. The HAART drugs mentioned above work inside the T cell, after it has been infected by the virus, by interrupting the virus' replica- tion. Unfortunately, thevirus de- velops resistance over time to these drugs; therefore, it requires the patient to contantly change to newer and better regimens. The fusion inhibitors' actions are different in that they prevent the virus from fusing to and enter- ing the T cell. In a very limited clinical trial of T-20, participants' viral loads were decreased and their T cells were increased. Additionally, no aller- Continued on page 34 DAVID AUGUST, D.O. BOARD CERTIFIED PSYCHIATRIST RED MILL CENTER 467 Highway One, Lewes 645-9076 FREE Health Seminar from Beebe Medical Center "Latex Allergies- Are You at Risk?" THURSDAY, AUGUST 27, 1998 SPEAKER: Donna Baker, R.N. Surgical Services Staff Nurse LOCATION: Beebe Medical Center's Gull House Rehoboth Beach (opposite Slra'ng Lake) TIME: 7:00 - 8:00 p.m. Beebe Medical Center This is a free seminar. Please call 645-3332 to register. 424 Savannah Rd., Lewes, DE A A A A I